“Our Marie Curie Fellows (Michela Comune from Italy and Josephine Blersch from Germany) from the ITN NanoDrug with the President of the European Commission, José Manuel Barroso, the President of CNC, Catarina Resende de Oliveira and Lino Ferreira Principal Investigator of Biomaterials and Stem cell based therapeutics Lab, recently awarded with a prestigious ERC Starting Grant.”
Maria Pereira and Lino Ferreira are co-authors of a recent publication in Science Translational Medicine. The work has been performed in collaboration with Jeff Karp and Pedro del Nido at Harvard. The work describes a bioinspired elastic, biodegradable and biocompatible tissue adhesive based on poly(glycerol-co-sebacate) acrylate (PGSA) that can be activated by UV light providing strong adhesion to dynamic tissues. PGSA presents better biocompatibility than cyanoacrylate adhesives and provided a hemostatic seal when applied to large blood vessels and cardiac wall defects. PGSA coated patches were attached on the interventricular septum in a chronic porcine beating heart model and resisted supraphysiologic pressures.